In this episode of the Untangle Podcast, host Patricia Karpas interviews Matt Zemon, editor and contributor to the book Psychedelics for Everyone: A Beginner’s Guide to Psychedelic Healing and Growing. Matt shares how a transformative guided psilocybin experience completely shifted his worldview—from a skeptic with minimal exposure to drugs to an advocate for the therapeutic potential of psychedelic medicine.

Drawing on his personal journey and academic background in psychology and neuroscience, Matt explains that his passion for psychedelics began when a trusted friend invited him to experience a guided magic mushroom session. This experience not only opened his mind but also helped him process deep-seated grief and reconnect with his inner self. He recounts a particularly profound moment during his journey, where he felt a healing connection with his late mother, underscoring the transformative power of these substances.

The conversation delves into how psychedelic medicines like psilocybin, MDMA, ketamine, ayahuasca, and ibogaine are being used today—not only for conditions such as depression, anxiety, and PTSD but also in end-of-life care and for breaking addictions. Matt emphasizes that while these substances can catalyze significant personal and emotional breakthroughs, their benefits are maximized only when paired with expert guidance and proper integration practices. He discusses the critical role of skilled facilitators who help create a safe environment and ensure that the insights gained during these sessions are integrated into everyday life.

Matt also touches on the broader cultural and historical context of psychedelics. He highlights that while many modern users are re-discovering these practices, the use of psychedelics spans centuries and is deeply rooted in various traditions around the world—from indigenous rituals in South America and Africa to lesser-known practices in Europe.

In addition to his work on the book, Matt shares his entrepreneurial journey with his venture “Happy,” which aims to reduce the high cost of ketamine therapy through telehealth. This initiative is part of his larger mission to address the widespread unhappiness and mental health challenges in today’s society.

Ultimately, the discussion is a blend of personal narrative, scientific insight, and practical guidance, offering listeners both a hopeful perspective on healing through psychedelics and a call for thoughtful, informed integration of these powerful tools into mental health care.