In this episode of High Performance Health, host Angela Foster speaks with Matt Zemon, an expert in psychology and neuroscience, about the role of psychedelics in mental health, healing anxiety and depression, and expanding human consciousness. Zemon shares his personal journey into psychedelics, beginning with a guided psilocybin experience that led him to explore the transformative potential of these substances. He discusses how psychedelics, including psilocybin, MDMA, and DMT, can facilitate deep healing by quieting negative thought patterns, fostering neuroplasticity, and helping individuals process trauma in a safe, controlled environment. The conversation covers the importance of “set and setting” when using psychedelics, the medical model versus spiritual approaches, and the growing research supporting their effectiveness in treating PTSD, depression, and existential distress in terminally ill patients. Zemon also explains how integration practices—such as mindfulness, gratitude, and intentional reflection—help maintain the insights gained from psychedelic experiences. Foster and Zemon delve into the broader implications of psychedelics, touching on societal conditioning, self-worth, and how mental models formed in childhood shape adult experiences. The episode highlights the potential of these substances to unlock deeper self-awareness and personal growth when used responsibly with professional guidance. For those interested in exploring psychedelics, Zemon recommends his books Psychedelics for Everyone and Beyond the Trip, which provide foundational knowledge and integration techniques.